Coming Soon

Canine Lymphoma
Lymphoma is one of the most commonly encountered cancers in the dog. The incidence of canine lymphoma has steadily increased with approximately 84 per 10,000 dogs diagnosed each year. This randomized, double-masked, placebo-controlled, GCP pivotal field study is evaluating the effectiveness and safety of verdinexor for the treatment of naïve or first relapse stages II, III and IV lymphoma in client owned dogs. Diagnosis of lymphoma must be confirmed by cytology or biopsy for the dog to be eligible for this study. Dogs will be randomized to receive the investigational veterinary product or a placebo treatment (tablets) to be administered with food twice weekly at least 72 hours apart for 8 weeks. After receiving treatment in-hospital on Day 0, the dog will be required to return to the study site on Days 7, 14, 28, 42, and 56 for follow up evaluation visits. Owners will be required to report and record abnormal daily observations and dosing using a phone app at home throughout the study.
- Your dog has naïve or first relapse lymphoma
- Your dog is over 1 year old and weighs more than 9kgs (~20lbs)
- Your dog has a diagnosis of lymphoma
You may be eligible to receive a $1,000 credit applied to your account at the clinical study site, additionally funding for the study includes:
Initial Study Screening
Scheduled Study Lab Work
Recheck visits and Exams
Managment of side effects
FRANKLIN, IN
RECRUITING
Performance of a New Point-of-care Rapid Test to Diagnose Pulmonary Coccidioidomycosis
Diagnosis of coccidioidomycosis in dogs is challenging due to the fact that the symptoms are not specific for this disease. Coccidioidomycosis can be diagnosed via a biopsy however the most common method is testing for antibodies to the fungus. These tests are often sent to third party labs delaying confirmation of the disease. This study looks to evaluate a potential point of care rapid test which would be able to provide a positive or negative result indicating the presence or absence of antibodies, respectively, within 30-60 minutes. The diagnosis of pulmonary coccidioidomycosis can be difficult because clinical signs overlap with many other respiratory tract disorders and dogs can have positive Valley Fever antibody titers without active clinical infection. Acute phase proteins are useful biomarkers for many other disorders and our hope is to determine whether they can facilitate making a diagnosis of pulmonary coccidioidomycosis in dogs. For additional details or questions please contact Dr. Jaffey (jjaffe@midwestern.edu).
- Your dog has a a confirmed or suspected novel diagnosis of pulmonary coccidioidomycosis
- Your dog has at least 1 respiratory sign
- Your dog has not received an anti-fungal treatment more than 7 days before enrollment
Free:
Coccidioides serologic testing
Repeat testing in 30 days if negative baseline results
Thoracic radiographs if performed at MWU
Repeat Valley Fever titer tests at 3 months
GLENDALE, AZ
RECRUITING

Canine Diabetes
Diabetes mellitus is an important health problem in both dogs and people. Type 1 diabetes (T1D) in people is caused by an attack of the body’s own immune system on cells in the pancreas. Diabetes in dogs is thought to be similar in some ways to T1D in people, but there is still much more to learn about the causes of diabetes in dogs as well as better ways to prevent and treat the disease. The purpose of this study is to learn more about metabolism and immune function in diabetic dogs.
- Your dog has been recently diagnosed with canine diabetes
- Your dog has other endocrine related disease or is a non-spayed female
Free Participation
Enrolled pets receive free:
- Bloodwork
- Urine Sample
- Repeated Vet Checkups
GAINESVILLE, FL
ENROLLING

DCM in Dobermans
Dilated Cardiomyopathy (DCM) is a disease of heart muscle that results in a decreased ability of the heart to pump blood. The prognosis for DCM is often poor, with a less than 50% survival rate one year after clinical signs develop, unless a reversible underlying cause is identified. There is no available cure for Dilated Cardiomyopathy, current techniques focus on extending survival time as long as possible. However the focus of this clinical trial is to evaluate a potential curative treatment for cardiomyopathy in the Doberman Pinscher.
- Your dog has been diagnosed with dilated cardiomyopathy
- Your dog has no other heart conditions
Free Participation
Enrolled pets receive free:
- Free participation
- bloodwork
- ECHO
- ECG
- Repeated vet checkups
GAINESVILLE, FL
ENROLLING

Dietary Trial for Cats with IBD or GI Lymphoma
The clinical signs in some cats with chronic enteropathy (chronic vomiting and/or diarrhea) can be reversed with dietary management using a specially formulated diet. It is not clear why some cats respond to diet, or what the optimal composition of the diet for cats with chronic enteropathy should be. We want to know if diets containing proteins that are selected to minimize immune responses and fortified in Vitamin B12 and natural anti-inflammatory agents (prebiotics and curcumin) are better than conventional diets for cats with chronic enteropathy.
- Any Cat with signs of chronic GI disease
ITHACA, NY
ENROLLING



Feline Diabetes
A new partnership between Anivive Lifesciences and Basepaws has formed to study the genetics of feline diabetes. Cats meeting the study criteria are eligible to receive complimentary genetic testing. Your participation in this study is an opportunity to support scientific exploration of the genes thought to be involved with diabetes. This information will help researchers develop new diagnostic tests, suggest possible preventative measures and explore new treatments for this common feline disease.
- Your cat has a confirmed diagnosis of diabetes mellitus for at least 6 months.
- Current diagnosis of acromegaly, hyperthyroidism, or hyperadrenocorticism
Enrolled pets receive:
- Free Genetic Test Kit
- Free Genetic Report
ENROLLING

FRANKLIN, IN
RECRUITING
Canine Lymphoma
Lymphoma is one of the most commonly encountered cancers in the dog. The incidence of canine lymphoma has steadily increased with approximately 84 per 10,000 dogs diagnosed each year. This randomized, double-masked, placebo-controlled, GCP pivotal field study is evaluating the effectiveness and safety of verdinexor for the treatment of naïve or first relapse stages II, III and IV lymphoma in client owned dogs. Diagnosis of lymphoma must be confirmed by cytology or biopsy for the dog to be eligible for this study. Dogs will be randomized to receive the investigational veterinary product or a placebo treatment (tablets) to be administered with food twice weekly at least 72 hours apart for 8 weeks. After receiving treatment in-hospital on Day 0, the dog will be required to return to the study site on Days 7, 14, 28, 42, and 56 for follow up evaluation visits. Owners will be required to report and record abnormal daily observations and dosing using a phone app at home throughout the study.
- Your dog has naïve or first relapse lymphoma
- Your dog is over 1 year old and weighs more than 9kgs (~20lbs)
- Your dog has a diagnosis of lymphoma
You may be eligible to receive a $1,000 credit applied to your account at the clinical study site, additionally funding for the study includes:
Initial Study Screening
Scheduled Study Lab Work
Recheck visits and Exams
Managment of side effects
GLENDALE, AZ
RECRUITING
Performance of a New Point-of-care Rapid Test to Diagnose Pulmonary Coccidioidomycosis
Diagnosis of coccidioidomycosis in dogs is challenging due to the fact that the symptoms are not specific for this disease. Coccidioidomycosis can be diagnosed via a biopsy however the most common method is testing for antibodies to the fungus. These tests are often sent to third party labs delaying confirmation of the disease. This study looks to evaluate a potential point of care rapid test which would be able to provide a positive or negative result indicating the presence or absence of antibodies, respectively, within 30-60 minutes. The diagnosis of pulmonary coccidioidomycosis can be difficult because clinical signs overlap with many other respiratory tract disorders and dogs can have positive Valley Fever antibody titers without active clinical infection. Acute phase proteins are useful biomarkers for many other disorders and our hope is to determine whether they can facilitate making a diagnosis of pulmonary coccidioidomycosis in dogs. For additional details or questions please contact Dr. Jaffey (jjaffe@midwestern.edu).
- Your dog has a a confirmed or suspected novel diagnosis of pulmonary coccidioidomycosis
- Your dog has at least 1 respiratory sign
- Your dog has not received an anti-fungal treatment more than 7 days before enrollment
Free:
Coccidioides serologic testing
Repeat testing in 30 days if negative baseline results
Thoracic radiographs if performed at MWU
Repeat Valley Fever titer tests at 3 months

GAINESVILLE, FL
ENROLLING
Canine Diabetes
Diabetes mellitus is an important health problem in both dogs and people. Type 1 diabetes (T1D) in people is caused by an attack of the body’s own immune system on cells in the pancreas. Diabetes in dogs is thought to be similar in some ways to T1D in people, but there is still much more to learn about the causes of diabetes in dogs as well as better ways to prevent and treat the disease. The purpose of this study is to learn more about metabolism and immune function in diabetic dogs.
- Your dog has been recently diagnosed with canine diabetes
- Your dog has other endocrine related disease or is a non-spayed female
Free Participation
Enrolled pets receive free:
- Bloodwork
- Urine Sample
- Repeated Vet Checkups

GAINESVILLE, FL
ENROLLING
DCM in Dobermans
Dilated Cardiomyopathy (DCM) is a disease of heart muscle that results in a decreased ability of the heart to pump blood. The prognosis for DCM is often poor, with a less than 50% survival rate one year after clinical signs develop, unless a reversible underlying cause is identified. There is no available cure for Dilated Cardiomyopathy, current techniques focus on extending survival time as long as possible. However the focus of this clinical trial is to evaluate a potential curative treatment for cardiomyopathy in the Doberman Pinscher.
- Your dog has been diagnosed with dilated cardiomyopathy
- Your dog has no other heart conditions
Free Participation
Enrolled pets receive free:
- Free participation
- bloodwork
- ECHO
- ECG
- Repeated vet checkups

ITHACA, NY
ENROLLING


Dietary Trial for Cats with IBD or GI Lymphoma
The clinical signs in some cats with chronic enteropathy (chronic vomiting and/or diarrhea) can be reversed with dietary management using a specially formulated diet. It is not clear why some cats respond to diet, or what the optimal composition of the diet for cats with chronic enteropathy should be. We want to know if diets containing proteins that are selected to minimize immune responses and fortified in Vitamin B12 and natural anti-inflammatory agents (prebiotics and curcumin) are better than conventional diets for cats with chronic enteropathy.
- Any Cat with signs of chronic GI disease

ENROLLING
Feline Diabetes
A new partnership between Anivive Lifesciences and Basepaws has formed to study the genetics of feline diabetes. Cats meeting the study criteria are eligible to receive complimentary genetic testing. Your participation in this study is an opportunity to support scientific exploration of the genes thought to be involved with diabetes. This information will help researchers develop new diagnostic tests, suggest possible preventative measures and explore new treatments for this common feline disease.
- Your cat has a confirmed diagnosis of diabetes mellitus for at least 6 months.
- Current diagnosis of acromegaly, hyperthyroidism, or hyperadrenocorticism
Enrolled pets receive:
- Free Genetic Test Kit
- Free Genetic Report
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